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Macular Amyloidosis

Macular Amyloidosis is  characterized by itchy symmetrical brown reticular maculas and the deposition of amyloid as small subepidermal globules.

Primary localized cutaneous amyloidosis refers to deposition of amyloid in apparently previously normal skin with no evidence of deposits in internal organs. There are three types of primary cutaneous amyloidosis: nodular cutaneous amyloidosis, macular amyloidosis and lichenoid amyloidosis. Macular and lichenoid forms of primary cutaneous amyloidosis occur relatively commonly and are associated with pruritus and friction. Macular amyloidosis is the commonest form of primary localized cutaneous amyloidosis; its etiology remains unclear. Macular amyloidosis is seen most frequently on the upper back, and is characterized by irregular pigmentation and pruritus
 
 

Symptoms of Macular amyloidosis

  • Flat discolored skin spots
  • Merging of skin spots to form patches
  • Patches of darkened skin

Treatment of Macular amyloidosis

  • Skin biopsy may be recommended.
  • Antihistamines are helpful in helping control the itching.
  • Topical steroids have been known to help control the itching.
  • Combination of potent steroids, salicylic acid  and bleaching agents can give partial results.
  • Treatment using ultraviolet B (UV-B) light has been useful in some cases.
  • Surgical methods like laser vaporization, dermabrasion, electrodesiccation and curettage are other treatments.

 

 

More Information on Amyloidosis
Primary Symptoms lichen macular

systemic

kidney

familial

coughing

picture secondary cardiac hereditary

 

 

 
 

 

 
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